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Reports of infants struggling from long-expression barbiturate publicity in utero provided the acute withdrawal syndrome of seizures and hyperirritability from birth into a delayed onset of up to 14 days. (See “Drug Abuse And Dependence” part.)Aged individuals may possibly respond to barbiturates with marked excitement, despair, and confusion.

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Nonetheless, determined by the accessible info, the window of vulnerability to these alterations is believed to correlate with exposures inside the third trimester of gestation with the very first many months of daily life, but may well prolong out to somewhere around 3 several years of age in people (see “Safety measures-Pregnancy and Pediatric

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